Quick detail:
Triiodothyronine is the active form of the thyroid hormone, thyroxine. T3 is the true hormone. Approximately 20% of triiodothyronine is secreted into the bloodstream directly by the thyroid gland. The remaining 80% is produced from conversion of thyroxine by organs such as the liver and kidneys.
 
T3 is not produced directly by your thyroid gland, is actually converted from the T4 thyroid hormone, it
has potent fat burning effects, and T3will enhance your body's ability to synthesize protein, even at very
low doses which can actually help add muscle. T3 when used in conjunction with  fragment will reducenitrogen retention, this is a fact, so if your looking to get big and ripped, you need to add in something else.
 
Cytomel (T3) is commonly used with  due to its significant impact on the body's metabolism as a whole. It is very important to understand that T3 is indiscriminate in its metabolism boosting properties - it will increase the metabolism of fats, carbohydrates, and protein all equally. The bodybuilding and athletic world is attracted to the use of T3 as a physique and/or performance enhancing drug because of its capability to distinctly boost the body's metabolism in the effort to metabolize body fat at a greater rate.

L-Triiodothyronine/T3 Specification:
L-Triiodothyronine/T3 Feature as Fat Loss:
Liothyronine is the most potent form of thyroid hormone. Chemically, it is nearly identical to triiodothyronine (T3). As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds.
 
T3 is a regulator of the oxidative metabolism of energy. When you take liothyronine sodium it will increase the uptake of nutrients into the mitochondria, which raises activity in the oxidative metabolic pathway. This causes everything to work harder within the organism and makes the body demand more fuel.
 
T3 in the body is responsible for regulating the uptake of various nutrients into cells and into the mitochondria of those cells in order to effectively become utilized for the production and consumption of energy.The mitochondria of every single cell in the body utilizes carbohydrates (primarily), fat, and even protein for the production of an energy source known as ATP (Adenosine Triphosphate). Through the intake of more T3, this production of ATP will increase, leading to an increased rate of energy consumption in the form of fats,carbohydrates, and protein. Hence, this is why the consumption of too much T3 without the use of  can result in muscle loss.
 
L-Triiodothyronine/T3 Feature as Bodybuilding Supplement:
The increase of ATP and metabolic activity leads the body to burn fat. This is why bodybuilders use T3 as a part of their anabolic stacks. Furthermore, T3 is popular among bodybuilders because it can help burn those stubborn 1 to 2% of body fat that won't come off through just diet and cardio.
 
Another interesting property of Cytomel is that it can enhance production.
 
L-Triiodothyronine/T3 Application:
* Promote gluconeogenesis,
* Increase utilization and mobilization of glycogen stores,
* Stimulate protein synthesis,
* Promote cell growth and differentiation,
* Aid in the development of the brain and CNS.
* Thyroid hormones play vital roles in regulating the body's metabolic rate, heart and digestive functions, muscle control, brain development and the maintenance of bones.
* Cytomel (T3) is also commonly combined with other fat loss agents in order to increase its overall effect, as it does work synergistically with other fat loss agents.


L-Triiodothyronine/T3 Effects:
1) Effects on Fat Metabolism:
T3 (or more specifically, thyroid hormones in general) are investigated for their interactions with fat mass since, in survey research, thyroid activity may be related to fat mass and BMI.  Some studies suggest a correlation whereas other suggest it does not exist for those with normal thyroid function.It is a contest field, as some studies do exist that suggest a relation even in those with normal thyroid function. These discrepancies may be due to the highly variable 'normal range' of thyroid hormones.
 
2) Effects on Muscle Tissue:
In obese subjects, a reduction in urinary nitrogen has been reported with T3 supplementation, and was additive to fasting's reduction in urinary nitrogen; suggesting a muscle preserving effect. These results have been replicated a short-term metabolic ward study at 100mcg daily, in four divided dosages. However, at least one study has noted an increase in urinary nitrogen after four weeks usage, in doses ranging from 0.36-1.01mcg/kg bodyweight.
 
3) Effects on Cognition:
Thyroid hormone status is correlated with cognition, and a lower level of thyroid hormones is related to depressive-like symptoms.
 
L-Triiodothyronine/T3 Dosage:
25-50 mcg initially (if cardiovascular disease is present, initial dose should be 10-20 mcg). Additional
doses may be given, to a total of at least 65 mcg/day (not to exceed 100 mcg/day). Doses should be at
least 4 hr but not more than 12 hr apart.
 
Cytomel (T3) does speed fat loss. As a guideline, for most 12.5 mcg/day is a conservative "supplement" sort of dosing that seems to have no detectable adverse effect on thyroid function at all.
25 mcg/day is a "supplement" sort of dosing that does have some inhibitory effect.
50 mcg/day is a reasonably conservative bb'ing sort of dose that, of course, is more inhibitory.
75 mcg/day is getting into more of a problem area;
100 mcg/day in many cases leads to loss of muscle size and strength.
 
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