Orlistat weight loss pills Orlistat for Loss Weight CAS: 96829-58-2

Basic Information:Product name: OrlistatCAS Numbers: 96829-58-2Appearance: white needle crystal or powderPacking specification: 1 kg/bagMelting point: 45°Purity: 98.0%Appearance: White or kind of white crystalline powder, soluble in water.Usage: Used for curing obesity.What is Orlistat?Orlistat is a white to off-wh

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Orlistat Fat Loss Pharmaceutical Orlistat for Loss Weight CAS: 96829-58-2

Basic Information:

Product name: Orlistat

CAS Numbers: 96829-58-2

Appearance: white needle crystal or powder

Packing specification: 1 kg/bag

Melting point: 45°

Purity: 98.0%

Appearance: White or kind of white crystalline powder, soluble in water.

Usage: Used for curing obesity.


What is Orlistat?

Orlistat is a white to off-white crystalline powder. Orlistat is practically insoluble in water, freely soluble in chloroform, and very soluble in methanol and ethanol. Orlistat has no pKa within the physiological pH range.
Orlistat is a drug that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food so that it can be absorbed into the body. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Orlistat blocks absorption of about 25% of the fat in a meal. The unabsorbed fat is excreted in the stool. The FDA approved Orlistat by prescription in 1999. 

Description:

Orlistat (also known as tetrahydrolipstatin) is a drug designed to treat obesity. It is marketed as a prescription drug under the trade by Roche in most countries, and is sold over-the-counter as Alli by GlaxoSmithKline in the United Kingdom and the United States.Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.

Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini.However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.


Application:

The effectiveness of orlistat in promoting weight loss is definite, though modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2-3 kilograms (4.4-6.6 lb) more than those not taking the drug over the course of a year.Orlistat also modestly reduces blood pressure, and appears to prevent the onset of type 2 diabetes, whether due to weight loss itself or to other effects; in a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.

Orlistat is notorious for its gastrointestinal side effects (sometimes referred to as treatment effects), which can include steatorrhea (oily, loose stools). These decrease with time, however, and are the most frequently reported adverse effects of the drug.In the United States and the European Union, orlistat is available for sale without a prescription. Over-the-counter approval was controversial in the United States, with consumer advocacy group Public Citizen repeatedly opposing it on safety and efficacy grounds.Generic formulations of orlistat are available in some countries. In Australia it is listed as an S3 medication, which means it's available over the counter in pharmacies.


COA:
 
TESTSSpecificationeResults
DescriptionWhite or almost crystalline powderWhite crystalline powder
IdentificationIRConforms
Specific rotation-33 -35°-34°
Loss on drying<0.5%0.35%
Melting point42-45ºC42-44ºC
Water<=2.0%0.25%
Residual solvents 
 
 
1260ppm
Assay(HPLC)>=96.0%(ON DRY BASIS)97.4%

 


Payment Information:
 
Pricenegotiable according to how many do you need
Payment TermTT/West Union /Bitcoin/ Money Gram
Delivery Timenormally 5-10 days by express
Shipping wayExpress(EMS,DHL,TNT,FedEX;HKDHL;EUB) Door to Door
Transport by air for large quantity.
Shipping TimeMost countries caan arrived within 3-10 days  


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--------------------------------  Additional Information  -------------------------------
Place of origin : China
Brand : SMQ
Certificate : ISO9001:2008, KOSHER, GMP, SGS
Production capacity : 1000 Kilograms/Month

--------------------------------  Delivery Information  ---------------------------------
Packing : Foil bag/tin or as your request
Payment : T/T, Western Union, MoneyGram
Port : Shanghai, Shenzhen, Hongkong
Shipment method : EMS, DHL, FeDex, UPS, etc
Leading  time : Within 24 hours after payment
Delivery time : Within 6 business days after payment (door to door service)
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