99% Bulk CB-03-01 17alpha Propionate CAS 19608-29-8

Product Name: CB-03-01
Synonyms: 17alpha-propionate;CB-03-1;17alpha-propio17-(1-oxopropoxy)pregn-4-ene-3,20-dione;CB-03-01 17alpha-propionate;CB-03-01;Cortexolone 17-alpha-propionate;17 alpha-propionate (CB-03-01);21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione
CAS:    19608-29-8
MF: C24H34O5
MW: 402.52
EINECS: 685-282-9
Appearance: White  powder
Assay: 99%
Shelf life: 24months
Storage: Cool&dry warehouse

CB-03-01 is the drug for the treatment of hair loss dwindled. It has same function and application with RU58841 and Setipiprant.
 
CB-03-01 is a molecule that acts at the level of the skin. The molecule has a unique mechanism that acts at the skin surface, and is quickly metabolized to free inactive cortexolone, a substance naturally found in the body. The molecule has been evaluated in a variety of animal models as well as initial human trials in Europe. The results of these studies demonstrate that CB-03-01 appears to have potent activity without significant local or systemic side effects.

Cortexolone 17α-propionate (developmental code name CB-03-01), or 11-deoxycortisol 17α-propionate, is a synthetic steroidal antiandrogen-specifically, an androgen receptor antagonist - which is used as a topical medication in the treatment of androgen-dependent conditions including acne vulgaris and androgenic alopecia (male-pattern hair loss). It is the C17α propionate ester of 11-deoxycortisol (cortexolone); C17α esters of 11-deoxycortisol were unexpectedly found to possess antiandrogen activity, and cortexolone 17α-propionate was selected for development based on its optimum drug profile.

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